ACE polymorphism in hispanic/latino patients with type 2 diabetes
Diabetes affects approximately 6-8% of the general population in the U.S. at a cost of over $130 billion annually. In Milwaukee County, there is an estimated 49,400 people (7.2%) diagnosed with diabetes and an additional 20,980 (3.1%) who remain undiagnosed. Diabetic nephropathy, a kidney condition related to diabetes, represents approximately 40% of new cases of end stage renal failure. There is considerable racial/ethnic variability in the condition. Hispanic/Latino patients are two to four times more likely to suffer complications. It is essential to examine the prevalence of the genetic makeup related to diabetic nephropathy to determine if it is contributing to a high incidence of complications. The Hispanic/Latino population might benefit by receiving more targeted interventions and drug therapy that could save health care dollars and reduce patient suffering.
This pilot project will enroll 15 Hispanic/Latino and 15 Caucasian individuals diagnosed with type 2 diabetes from Aurora Health Care Family Care Practice clinics. The study includes both English speakers and non-English speakers.
October 2007 - December 2010
Wisconsin Network for Health Research
University of Wisconsin Hospitals and Clinics
Gundersen Lutheran Medical Foundation
Marshfield Clinic Research Foundation
Aurora Health Care/Center for Urban Population Health
Aurora UW Medical Group
Jake Bidwell, MD
Dennis Baumgardner, MD
John Brill, MD, MPH
Rebecca Schultz, RN, FNP
Center for Urban Population Health
Jennifer Evertsen, MS
Jennifer Kroll, BA
Ruth Perez, BA
Amanda Joyce, BS
To learn more, contact:
National Kidney Foundation of Wisconsin and Wisconsin Lions Foundation. The 2008 Burden of Diabetes in Wisconsin. January 2008.