Pilot Study to Implement a Coumadin/Warfarin Dosing Calculator
Coumadin is a commonly used drug that prevents blood clotting. However, there is a high rate of side effects for patients on Coumadin. An individual’s ideal Coumadin dose varies based on his or her personal characteristics. Some of this variability may be attributed to an individual’s genetic makeup. Marshfield Clinic Research Foundation has previously developed a dosing model that explains about 56% of the dose variability. The dosing calculator has yet to be implemented in real time. Testing the new methods in real time will help determine the feasibility of using the dosing calculator to administer Coumadin to patients who are newly diagnosed with conditions requiring Coumadin therapy.
Patients who are newly diagnosed with a condition that requires Coumadin therapy.
February 2007 - January 2009
Aurora Health Care
Matthew Tector, PhD
Aurora UW Medical Group
Dennis Baumgardner, MD
Center for Urban Population Health
Jennifer Evertsen, MS
Melissa Lemke, BA