TReating Children to Prevent Exacerbations of Asthma (TREXA)
Since asthma is the most common chronic childhood disease in the U.S., the CARE Network was established to evaluate treatments for children with asthma. The Childhood Asthma Research and Education (CARE) Network was established in 1999 by the National Heart, Lung and Blood Institute (NHLBI). Five clinical centers and a data-coordinating center were selected to participate in this research network. The CARE Network is conducting several studies for children with asthma and they have been sharing their findings with the health care community.
Children with mild asthma are often prescribed daily-inhaled corticosteroids (ICS), however, it is not clear how long these children must continue to take these. Keeping children on daily doses of ICS when their asthma is under good control could be costly, both in terms of cost of medication as well as potential side effects and the extra burden daily doses place on parents and children. No systematic studies have addressed this issue. This protocol determined how to safely and systematically wean children off of ICS controllers after long periods of wellness.
This study collected empirical data on two questions about the treatment of childhood asthma:
Served In Wisconsin, 56 children (age 6-17 years) with mild persistent asthma will be enrolled. Nationwide, 280 children will be enrolled in this study.
Individual study participation lasts for 44 weeks; the study is slated to end in early 2009.
Aurora UW Medical Group
Elizabeth Bade, MD
University of Wisconsin-Madison
Robert Lemanske, MD
Partners (CARE Network Sites)
For more information contact:
Ruth Perez, BA
(414) 219-CARE (2273)